Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 18/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469804 | 0.87 | HTT (0.46) | — | |
| SCHEMBL3848659 | 0.85 | MEN1 (0.52) | RXFP1 | |
| SCHEMBL4459109 | 0.85 | RAF1 (0.41) | RXFP1 | |
| SCHEMBL4462942 | 0.85 | FADS1 (0.49) | P2RX1 | |
| SCHEMBL27919273 | 0.82 | FADS1 (0.51) | RXFP1 | |
| SCHEMBL4464511 | 0.80 | MAPT (0.44) | — | |
| SCHEMBL1792255 | 0.80 | RAF1 (0.57) | RXFP1 | |
| SCHEMBL1469077 | 0.77 | RXFP1 (0.49) | RXFP1P2RX1 | |
| SCHEMBL4473204 | 0.77 | NPC1 (0.41) | RXFP1 | |
| SCHEMBL3855951 | 0.74 | NPSR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959516-B | Combination therapy comprising quinoxaline PI3K alpha inhibitors for the treatment of cancer | EXELIXIS INC | 2013-05-08 | — | — | CN | disclosed |