Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 7/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22189937 | 1.00 | GPR4 (0.39) | GPR4CTSKL3MBTL3L3MBTL1HRH3 | |
| SCHEMBL28823410 | 0.99 | GPR4 (0.37) | GPR4CTSKL3MBTL3L3MBTL1GRIN2B | |
| SCHEMBL27919676 | 0.99 | GPR4 (0.37) | GPR4CTSKL3MBTL3L3MBTL1GRIN2B | |
| SCHEMBL28784755 | 0.90 | ACVR1 (0.33) | GPR4CTSKL3MBTL1GRIN2B | |
| SCHEMBL27768013 | 0.90 | ACVR1 (0.33) | GPR4CTSKL3MBTL1GRIN2B | |
| SCHEMBL27789436 | 0.90 | APP (0.34) | HRH3GRIN2B | |
| SCHEMBL28039255 | 0.90 | APP (0.34) | HRH3GRIN2B | |
| SCHEMBL27901893 | 0.88 | LTA4H (0.34) | HRH3GRIN2B | |
| SCHEMBL467878 | 0.87 | GPR4 (0.46) | GPR4CTSKL3MBTL3L3MBTL1HRH3 | |
| SCHEMBL467638 | 0.85 | GPR4 (0.44) | GPR4CTSKL3MBTL3L3MBTL1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622248-B | N3-heteroaryl substituted triazoles and n5-heteroaryl substituted triazoles useful as AXL inhibitors | RIGEL PHARMACEUTICALS INC | 2013-04-17 | — | — | CN | claimed |
| CN-101622248-B | N3-heteroaryl substituted triazoles and n5-heteroaryl substituted triazoles useful as AXL inhibitors | RIGEL PHARMACEUTICALS INC | 2013-04-17 | — | — | CN | disclosed |