Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 5/20 | 1.00 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | PRKCG | P05129 | 1/20 | 0.52 |
| ▸ | PRKCB | P05771 | 1/20 | 0.52 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | PRKCH | P24723 | 1/20 | 0.52 |
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.52 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789163 | 1.00 | SERPINE1 (1.00) | SERPINE1SYNJ2DYRK1APRKD3PRKCG | |
| SCHEMBL15069951 | 1.00 | SERPINE1 (1.00) | SERPINE1SYNJ2DYRK1APRKD3PRKCG | |
| SCHEMBL15052516 | 0.96 | SERPINE1 (0.93) | SERPINE1SYNJ2DYRK1APRKD3PRKCG | |
| SCHEMBL3654334 | 0.92 | SERPINE1 (0.86) | SERPINE1SYNJ2DYRK1APRKD3PRKCG | |
| SCHEMBL12120882 | 0.92 | SERPINE1 (0.84) | SERPINE1SYNJ2DYRK1APRKD3PRKCG | |
| SCHEMBL10016123 | 0.92 | SERPINE1 (0.84) | SERPINE1SYNJ2DYRK1APRKD3PRKCG | |
| SCHEMBL10016129 | 0.91 | SERPINE1 (0.82) | SERPINE1SYNJ2DYRK1APRKD3PRKCG | |
| SCHEMBL157443 | 0.85 | SERPINE1 (0.86) | SERPINE1SYNJ2DYRK1APRKD3PRKCG | |
| SCHEMBL28457118 | 0.84 | SERPINE1 (0.83) | SERPINE1DYRK1APRKD3PRKCGPRKCB | |
| SCHEMBL28462463 | 0.84 | SERPINE1 (0.83) | SERPINE1DYRK1APRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105592892-B | Compositions comprising gallic acid esters and gallic acid amides | 高露洁-棕榄公司 | 2020-04-10 | — | — | CN | claimed |
| EP-2794030-B1 | COMPOSITIONS COMPRISING GALLATES AND GALLAMIDES | COLGATE PALMOLIVE CO (US) | 2017-03-15 | — | — | EP | claimed |
| US-20130164228-A1 | COMPOSITIONS COMPRISING GALLATES AND GALLAMIDES | COLGATE-PALMOLIVE COMPANY (US) | 2013-06-27 | — | — | US | claimed |
| US-11976305-B2 | Lassa vaccine | INSTITUT PASTEUR (FR) | 2024-05-07 | — | — | US | disclosed |
| CN-105592892-B | Compositions comprising gallic acid esters and gallic acid amides | 高露洁-棕榄公司 | 2020-04-10 | — | — | CN | disclosed |
| EP-2794030-B1 | COMPOSITIONS COMPRISING GALLATES AND GALLAMIDES | COLGATE PALMOLIVE CO (US) | 2017-03-15 | — | — | EP | disclosed |
| US-9527878-B2 | Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-12-27 | — | — | US | disclosed |
| US-9527878-B2 | Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-12-27 | — | — | US | disclosed |
| US-9527878-B2 | Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-12-27 | — | — | US | disclosed |
| US-9399631-B2 | Polyphenol proteasome inhibitors, synthesis, and methods of use | UNIVERSITY OF SOUTH FLORIDA (US) | 2016-07-26 | — | — | US | disclosed |
| US-20160009748-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF TO MODULATE LIPID METABOLISM | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-01-14 | — | — | US | disclosed |
| US-20100137194-A1 | Plasminogen Activator Inhibitor-1 Inhibitors and Methods of Use Thereof to Modulate Lipid Metabolism | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2010-06-03 | — | — | US | disclosed |
| US-20100137194-A1 | Plasminogen Activator Inhibitor-1 Inhibitors and Methods of Use Thereof to Modulate Lipid Metabolism | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2010-06-03 | — | — | US | disclosed |
| US-20090011055-A1 | Plasminogen Activator Inhibitor-1 Inhibitors And Methods Of Use Thereof To Modulate Lipid Metabolism | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-01-08 | — | — | US | disclosed |
| US-20090011055-A1 | Plasminogen Activator Inhibitor-1 Inhibitors And Methods Of Use Thereof To Modulate Lipid Metabolism | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-01-08 | — | — | US | disclosed |
| US-20090011055-A1 | Plasminogen Activator Inhibitor-1 Inhibitors And Methods Of Use Thereof To Modulate Lipid Metabolism | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-01-08 | — | — | US | disclosed |
| WO-2008131047-A2 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF TO MODULATE LIPID METABOLISM | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-10-30 | — | — | WO | disclosed |
| US-7358383-B2 | Polyphenol proteasome inhibitors, synthesis, and methods of use | UNIVERSITY OF SOUTH FLORIDA (US) | 2008-04-15 | — | — | US | disclosed |
| US-7358383-B2 | Polyphenol proteasome inhibitors, synthesis, and methods of use | UNIVERSITY OF SOUTH FLORIDA (US) | 2008-04-15 | — | — | US | disclosed |
| US-20080015248-A1 | Polyphenol proteasome inhibitors, synthesis, and methods of use | DOU Q P | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130164228-A1 | COMPOSITIONS COMPRISING GALLATES AND GALLAMIDES | CUTA, PGC, GTF3C5 | SERPINE1 3370/4885SYNJ2 1953/4885DYRK1A 3721/4885 |
| US-20100137194-A1 | Plasminogen Activator Inhibitor-1 Inhibitors and Methods of Use Thereof to Modulate Lipid Metabolism | SERPINE1, PLAT, SERPINB1 | SERPINE1 1/4885SYNJ2 3116/4885DYRK1A 4652/4885 |
| US-20160009748-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF TO MODULATE LIPID METABOLISM | SERPINE1, PLAT, SERPINB1 | SERPINE1 1/4885SYNJ2 3116/4885DYRK1A 4652/4885 |
| US-20090011055-A1 | Plasminogen Activator Inhibitor-1 Inhibitors And Methods Of Use Thereof To Modulate Lipid Metabolism | SERPINE1, PLAT, SERPINB1 | SERPINE1 1/4885SYNJ2 3116/4885DYRK1A 4652/4885 |
| US-20080015248-A1 | Polyphenol proteasome inhibitors, synthesis, and methods of use | PSMC1, PSMB5, PSMC5 | SERPINE1 431/4885SYNJ2 2224/4885DYRK1A 4227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.