SCHEMBL27904261

SCHEMBL27904261

O=C1c2ccccc2C(=O)c2cc(C3CNCCO3)ccc21

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.54
DRD3 P35462 1/20 0.54
HTR1A P08908 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27997979 0.81 DRD2 (0.50) DRD2DRD3HTR1A
SCHEMBL29234863 0.79 DRD2 (0.52) DRD2DRD3HTR1A
SCHEMBL18623590 0.78 TSHR (0.47)
SCHEMBL27997986 0.78 ALDH1A1 (0.47)
SCHEMBL27904263 0.76 DRD2 (0.43) DRD2DRD3HTR1A
SCHEMBL2599485 0.76 CYP2D6 (0.65) DRD2DRD3HTR1A
SCHEMBL27403589 0.76 CYP2D6 (0.65) DRD2DRD3HTR1A
SCHEMBL28792767 0.75 DRD2 (0.51) DRD2DRD3HTR1A
SCHEMBL31749847 0.75 DRD2 (0.48) DRD2DRD3HTR1A
SCHEMBL31749313 0.75 DRD2 (0.48) DRD2DRD3HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103135374-B Method, handle box, electronic photographing device and the phthalocyanine crystal of electrophotographic photosensitive element, production electrophotographic photosensitive element CANON K. K. (JP) 2016-05-11 CN disclosed
CN-103135374-A Electrophotographic photosensitive member, method of producing electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and phthalocyanine crystal CANON KK 2013-06-05 CN disclosed