SCHEMBL27904263

SCHEMBL27904263

O=C1c2ccccc2C(=O)c2c1cccc2C1CNCCO1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.43
DRD3 P35462 1/20 0.43
HTR1A P08908 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 2/20 0.39
HTR2A P28223 2/20 0.39
ADORA2A P29274 1/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP3A5 P20815 2/20 0.38
CYP3A7 P24462 2/20 0.38
CYP2C19 P33261 2/20 0.38
PDK4 Q16654 2/20 0.38
CYP3A43 Q9HB55 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29016821 0.77 L3MBTL1 (0.44) L3MBTL1MAPTMEN1NPC1RAB9A
SCHEMBL27904261 0.76 DRD2 (0.54) DRD2DRD3HTR1A
SCHEMBL1538935 0.75 DRD2 (0.52) DRD2DRD3HTR1AHTR2A
SCHEMBL28689779 0.73 DRD2 (0.42) DRD2DRD3HTR1AHTR2A
SCHEMBL28442591 0.73 DRD2 (0.34) DRD2DRD3HTR1AMAPTMEN1
SCHEMBL322882 0.72 HTR6 (0.43) DRD2DRD3HTR1AHTR2A
SCHEMBL29151771 0.72 HTR2C (0.50) DRD2DRD3HTR1AHTR2C
SCHEMBL2599486 0.72 DRD2 (0.49) DRD2DRD3HTR1AHTR2A
SCHEMBL7963983 0.71 DRD2 (0.46) DRD2DRD3HTR1AHTR2A
SCHEMBL2787499 0.71 HTR1A (0.47) DRD2DRD3HTR1AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103135374-B Method, handle box, electronic photographing device and the phthalocyanine crystal of electrophotographic photosensitive element, production electrophotographic photosensitive element CANON K. K. (JP) 2016-05-11 CN disclosed
CN-103135374-A Electrophotographic photosensitive member, method of producing electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and phthalocyanine crystal CANON KK 2013-06-05 CN disclosed