Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791994 | 0.89 | DPP4 (0.38) | KDM4EALDH1A1GAABCL2L11BCL2 | |
| SCHEMBL2790320 | 0.88 | KDM4E (0.42) | FPR2ITGB3ITGA2BKDM4EALDH1A1 | |
| SCHEMBL2789762 | 0.88 | ITGB1 (0.31) | ITGB3ITGA2BKDM4EALDH1A1GAA | |
| SCHEMBL2789237 | 0.80 | CNR2 (0.37) | FPR2ITGB3ITGA2BALDH1A1GAA | |
| SCHEMBL7900939 | 0.79 | TP53 (0.37) | ITGB3ITGA2BKDM4EMEN1KMT2A | |
| SCHEMBL2789091 | 0.78 | NMT1 (0.36) | KDM4EALDH1A1GAAPDE2AREN | |
| SCHEMBL2791424 | 0.78 | DPP4 (0.35) | KDM4EALDH1A1GAAPDE2AREN | |
| SCHEMBL2789311 | 0.78 | DPP4 (0.35) | KDM4EALDH1A1GAAPDE2A | |
| SCHEMBL2790530 | 0.78 | GFER (0.39) | FPR2ITGB3ITGA2BKDM4EALDH1A1 | |
| SCHEMBL2788340 | 0.77 | DPP4 (0.34) | KDM4EALDH1A1GAAPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |