Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790508 | 0.88 | FPR2 (0.34) | ITGB1ITGA4ITGB3ITGA2BKDM4E | |
| SCHEMBL2791052 | 0.88 | PROKR1 (0.34) | — | |
| SCHEMBL2814040 | 0.82 | CNR2 (0.34) | ALDH1A1 | |
| SCHEMBL2814043 | 0.82 | CNR2 (0.34) | ALDH1A1 | |
| SCHEMBL2790813 | 0.79 | PROKR1 (0.36) | ITGB3ITGA2BTACR2ALDH1A1 | |
| SCHEMBL2791994 | 0.78 | DPP4 (0.38) | KDM4EALDH1A1GAA | |
| SCHEMBL2790320 | 0.77 | KDM4E (0.42) | ITGB3ITGA2BKDM4EALDH1A1 | |
| SCHEMBL2790479 | 0.76 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL2790483 | 0.76 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL7898296 | 0.75 | CNR2 (0.33) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |