Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.38 |
| ▸ | NMT1 | P30419 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790508 | 0.89 | FPR2 (0.34) | KDM4EALDH1A1GAABCL2L11BCL2 | |
| SCHEMBL2789091 | 0.88 | NMT1 (0.36) | DPP4DPP7DPP8DPP9NMT1 | |
| SCHEMBL2789311 | 0.88 | DPP4 (0.35) | DPP4DPP7DPP8DPP9NMT1 | |
| SCHEMBL2791424 | 0.88 | DPP4 (0.35) | DPP4DPP7DPP8DPP9NMT1 | |
| SCHEMBL2788340 | 0.87 | DPP4 (0.34) | DPP4DPP7DPP8DPP9NMT1 | |
| SCHEMBL2789653 | 0.86 | NPC1 (0.39) | DPP4DPP7DPP8DPP9NMT1 | |
| SCHEMBL2812730 | 0.86 | PROKR1 (0.39) | DPP4DPP7DPP8DPP9NMT1 | |
| SCHEMBL2789378 | 0.84 | PIK3CA (0.33) | DPP4DPP7DPP8DPP9NMT1 | |
| SCHEMBL2789762 | 0.78 | ITGB1 (0.31) | KDM4EALDH1A1GAA | |
| SCHEMBL2791810 | 0.77 | USP30 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |