SCHEMBL27906006

SCHEMBL27906006

C=C(Cc1cccc(-c2cccc(CC(=C)c3ccccc3)c2)c1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.43
AGXT P21549 1/20 0.43
CFD P00746 1/20 0.42
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
KMO O15229 1/20 0.41
BCL2 P10415 1/20 0.41
FAAH O00519 1/20 0.40
NAAA Q02083 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38664634 0.87 KMO (0.48) NR4A2AGXTCFDKMOPRSS1
SCHEMBL163962 0.83 MAOA (0.50) MAOAMAOB
SCHEMBL13381340 0.81 FOLH1 (0.58) NR4A2
SCHEMBL28910971 0.80 SRD5A2 (0.52)
SCHEMBL11015736 0.80 LMNA (0.55) MAOAMAOB
SCHEMBL5932002 0.77 AGXT (0.47) NR4A2AGXTBCL2FAAHNAAA
SCHEMBL1515758 0.76 SRD5A2 (0.61) NR4A2KMOBCL2FAAHNAAA
SCHEMBL25728438 0.75 MEN1 (0.50) MAOAMAOB
SCHEMBL30209486 0.74 GPR52 (0.47) NR4A2MAOAMAOB
SCHEMBL28552020 0.74 GPR52 (0.47) NR4A2MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102884035-B Synthesis of magnolol and its analogous compounds COLGATE-PALMOLIVE CO. (US) 2016-01-20 CN claimed
CN-102884035-A Synthesis of magnolol and its analogous compounds INDIAN INST OF CHEMICAL TECHNOLOGY (IN) 2013-01-16 CN claimed
CN-104135992-B Oral care composition 高露洁-棕榄公司 2017-03-29 CN disclosed
CN-102884035-B Synthesis of magnolol and its analogous compounds COLGATE-PALMOLIVE CO. (US) 2016-01-20 CN disclosed
CN-104135992-A Oral care compositions COLGATE PALMOLIVE CO 2014-11-05 CN disclosed
CN-102884035-A Synthesis of magnolol and its analogous compounds INDIAN INST OF CHEMICAL TECHNOLOGY (IN) 2013-01-16 CN disclosed