Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771264 | 0.82 | HTR2A (0.44) | POLBMAPTKDM4ERECQLL3MBTL1 | |
| SCHEMBL27486901 | 0.81 | GPR84 (0.33) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL27369292 | 0.81 | GPR84 (0.44) | MAPTKDM4EGPR84FFAR1HTR2A | |
| SCHEMBL27965809 | 0.80 | CYP2A6 (0.35) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL27524231 | 0.80 | NR4A2 (0.46) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL27906752 | 0.80 | FFAR1 (0.43) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL28678155 | 0.78 | HTR2A (0.45) | MAPTHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL28293156 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KMT2AGAA | |
| SCHEMBL27908791 | 0.77 | HTR2A (0.35) | MAPTKDM4EGPR84FFAR1HTR2A | |
| SCHEMBL28818816 | 0.76 | SLC6A4 (0.39) | MAPTGPR84FFAR1HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-A | A kind of synthetic method of 2- substituted indole derivative | 中国医学科学院药物研究所 | 2019-05-14 | — | — | CN | disclosed |