SCHEMBL27907642

SCHEMBL27907642

Nc1ccc2c(c1)C(=O)c1cc(O)c(O)cc1C2=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.69
NPC1 O15118 2/20 0.69
RAB9A P51151 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
MAPK1 P28482 2/20 0.69
TDP1 Q9NUW8 2/20 0.69
TP53 P04637 1/20 0.69
CYP3A4 P08684 1/20 0.69
TSHR P16473 1/20 0.69
MCL1 Q07820 7/20 0.61
BCL2 P10415 6/20 0.61
PTPRC P08575 2/20 0.61
MEN1 O00255 2/20 0.61
LMNA P02545 2/20 0.61
POLB P06746 2/20 0.61
KMT2A Q03164 2/20 0.61
NPSR1 Q6W5P4 2/20 0.61
APAF1 O14727 1/20 0.61
TDP2 O95551 1/20 0.61
NSD2 O96028 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3135129 0.89 NPC1 (0.86) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL516210 0.89 NPC1 (0.86) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL28005394 0.86 NPC1 (0.82) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL9019017 0.84 NPC1 (0.78) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL31087632 0.84 NPC1 (0.78) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL30350052 0.84 NPC1 (0.77) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL9019051 0.84 NPC1 (0.77) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL864582 0.84 NPC1 (0.77) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL6659611 0.83 ALDH1A1 (0.59) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
Anthraquinone SCHEMBL23363689 0.82 NPC1 (1.00) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103137946-A Anthraquinone lithium battery positive pole and preparation method thereof DENG LIJUAN 2013-06-05 CN disclosed