Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907690 | 0.81 | KCNK3 (0.37) | KCNK3KCNK9GAAAPPF2R | |
| SCHEMBL6736066 | 0.79 | AR (0.33) | KCNK3KCNK9PPARGPPARDPPARA | |
| SCHEMBL6737194 | 0.78 | KCNK3 (0.39) | KCNK3KCNK9GAAF2RPPARG | |
| SCHEMBL27643692 | 0.77 | CYP2D6 (0.36) | KCNK3KCNK9GAAPPARGPPARD | |
| SCHEMBL6195357 | 0.75 | KCNK3 (0.34) | KCNK3KCNK9GAAHDAC3HDAC1 | |
| SCHEMBL6195588 | 0.75 | KCNK3 (0.32) | KCNK3KCNK9PPARGPPARDPPARA | |
| SCHEMBL27624241 | 0.72 | KCNK3 (0.44) | KCNK3KCNK9GAAAPPPPARG | |
| SCHEMBL6193631 | 0.71 | MEN1 (0.37) | KCNK3KCNK9GAAPPARGPPARD | |
| SCHEMBL5608059 | 0.69 | KCNK3 (0.38) | KCNK3KCNK9GAAPPARGPPARD | |
| SCHEMBL21524345 | 0.69 | KCNK3 (0.40) | KCNK3KCNK9F2RPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040072839-A1 | 1-Phenylalkylpiperazines | RECORDATI S.A. (CH) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072839-A1 | 1-Phenylalkylpiperazines | HTR5A, HTR1A, HTR1D | KCNK3 1292/4885KCNK9 2812/4885GAA 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.