Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907544 | 0.75 | SLC16A3 (0.59) | SMN1; SMN2MALT1SLC16A3SLC16A1 | |
| SCHEMBL27890741 | 0.70 | CA9 (0.55) | PDPK1MALT1SLC16A3SLC16A1 | |
| SCHEMBL7308514 | 0.70 | GAA (0.51) | ALOX5MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1988198 | 0.69 | RPA1 (0.58) | PDPK1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28800997 | 0.69 | FABP3 (0.47) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL20786115 | 0.68 | RPA1 (0.64) | MEN1KMT2A | |
| SCHEMBL11515884 | 0.67 | ALOX5 (0.71) | ALOX5MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31517697 | 0.67 | ALOX5 (0.71) | ALOX5MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13239861 | 0.66 | NPC1 (0.62) | ALOX5ALDH1A1HTTSLC16A3SLC16A1 | |
| SCHEMBL28905375 | 0.66 | HTR7 (0.67) | ALOX5MEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101906105-B | Pyrazolo (1,5-a) pyrimidone derivative as well as drug combination thereof and application thereof | UNIV HEBEI MEDICAL | 2013-01-16 | — | — | CN | disclosed |