Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 5/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30081441 | 0.84 | GPR3 (0.54) | GPR3CHRM5ALDH1A1MAPK1POLB | |
| SCHEMBL27907854 | 0.81 | ALOX5AP (0.51) | GPR3METAP2CHRM5KIF11IGF2BP2 | |
| SCHEMBL16429063 | 0.81 | ALOX5 (0.55) | GPR3METAP2CHRM5ALDH1A1THRB | |
| SCHEMBL28177887 | 0.79 | SCN5A (0.51) | GPR3METAP2CHRM5KIF11CHRM1 | |
| SCHEMBL27926260 | 0.79 | GPR3 (0.49) | GPR3METAP2CHRM5THRBKIF11 | |
| SCHEMBL16099410 | 0.79 | GPR3 (0.49) | GPR3METAP2CHRM5ALDH1A1GAA | |
| SCHEMBL4150746 | 0.79 | ALDH1A1 (0.52) | GPR3ALDH1A1MAPK1KIF11FFAR1 | |
| SCHEMBL17782985 | 0.78 | PTPN1 (0.54) | GPR3ALDH1A1MAPK1 | |
| SCHEMBL28628830 | 0.77 | METAP2 (0.49) | GPR3METAP2CHRM5KIF11IGF2BP2 | |
| Water SCHEMBL9853421 | 0.77 | PTPN1 (0.53) | GPR3ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103180300-A | Process for producing pyridazinone compound and intermediate thereof | SUMITOMO CHEMICAL CO | 2013-06-26 | — | — | CN | disclosed |