Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792270 | 1.00 | KMT2A (0.44) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL2791618 | 1.00 | KMT2A (0.44) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL8396776 | 0.85 | TSHR (0.45) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL25890673 | 0.79 | POLB (0.41) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL2794043 | 0.78 | HPGD (0.39) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL2794802 | 0.78 | HPGD (0.39) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL12984864 | 0.77 | HPGD (0.38) | KMT2AMEN1TSHRPOLBHPGD | |
| SCHEMBL28307954 | 0.76 | PGR (0.46) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL11238917 | 0.76 | PGR (0.46) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL11238921 | 0.76 | PGR (0.46) | KMT2AMEN1PLA2G1BHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065794-A1 | Wrinkle-preventing and improving composition | SHISEIDO COMPANY, LTD. (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20100168468-A1 | WRINKLE-PREVENTING AND IMPROVING COMPOSITION | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-07-01 | — | — | US | disclosed |
| EP-1908454-A1 | WRINKLE-PREVENTIVE/AMELIORATING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2008-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168468-A1 | WRINKLE-PREVENTING AND IMPROVING COMPOSITION | COL1A1, COL2A1, COL14A1 | KMT2A 2892/4885MEN1 3089/4885PLA2G1B 2218/4885 |
| US-20110065794-A1 | Wrinkle-preventing and improving composition | COL1A1, COL2A1, COL14A1 | KMT2A 2892/4885MEN1 3089/4885PLA2G1B 2218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.