Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2794043 | 1.00 | HPGD (0.39) | HPGDALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL12984494 | 0.88 | KMT2A (0.46) | HPGDALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL12984864 | 0.86 | HPGD (0.38) | HPGDALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL12984488 | 0.85 | KMT2A (0.47) | HPGDALDH1A1KMT2AMEN1PLA2G1B | |
| SCHEMBL12984378 | 0.84 | ALDH1A1 (0.44) | HPGDALDH1A1KMT2AMEN1HDAC1 | |
| SCHEMBL12982636 | 0.82 | ALDH1A1 (0.39) | HPGDALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL12983744 | 0.82 | LMNA (0.44) | HPGDALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL12984499 | 0.81 | KMT2A (0.53) | ALDH1A1TSHRKMT2AMEN1KCNH2 | |
| SCHEMBL12985410 | 0.81 | LMNA (0.44) | HPGDALDH1A1KMT2AKDM4EHTT | |
| SCHEMBL12983790 | 0.80 | LMNA (0.39) | HPGDALDH1A1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2514402-B1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEM IND INC (JP) | 2016-08-31 | — | — | EP | disclosed |
| US-9414998-B2 | Preventing or ameliorating agent for pigmentation | POLA CHEMICAL INDUSTRIES INC. (JP) | 2016-08-16 | — | — | US | disclosed |
| US-20140322150-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-10-30 | — | — | US | disclosed |
| EP-2514402-A1 | PROPHYLACTIC OR AMELIORATING AGENT FO PIGMENTATION | Pola Chemical Industries Inc. (JP) | 2012-10-24 | — | — | EP | disclosed |
| US-20120258063-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2012-10-11 | — | — | US | disclosed |
| US-20110065794-A1 | Wrinkle-preventing and improving composition | SHISEIDO COMPANY, LTD. (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20100168468-A1 | WRINKLE-PREVENTING AND IMPROVING COMPOSITION | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-07-01 | — | — | US | disclosed |
| EP-1908454-A1 | WRINKLE-PREVENTIVE/AMELIORATING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2008-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140322150-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, MITF | HPGD 636/4885ALDH1A1 117/4885TSHR 1691/4885 |
| US-20100168468-A1 | WRINKLE-PREVENTING AND IMPROVING COMPOSITION | COL1A1, COL2A1, COL14A1 | HPGD 1056/4885ALDH1A1 2131/4885TSHR 2887/4885 |
| US-20120258063-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, MITF | HPGD 636/4885ALDH1A1 117/4885TSHR 1691/4885 |
| US-20110065794-A1 | Wrinkle-preventing and improving composition | COL1A1, COL2A1, COL14A1 | HPGD 1056/4885ALDH1A1 2131/4885TSHR 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.