Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27891655 | 0.84 | PARP1 (0.44) | ALDH1A1PARP1LMNAALOX12KDM4E | |
| SCHEMBL29103150 | 0.84 | PARP1 (0.47) | ALDH1A1PARP1KDM4EKMT2A | |
| SCHEMBL30170409 | 0.79 | KDM4E (0.68) | ALDH1A1NR4A1NR4A2NR4A3LMNA | |
| SCHEMBL7143621 | 0.79 | KDM4E (0.68) | ALDH1A1NR4A1NR4A2NR4A3LMNA | |
| SCHEMBL1697008 | 0.79 | ALDH1A1 (0.50) | ALDH1A1NR4A1NR4A2NR4A3PARP1 | |
| SCHEMBL5319765 | 0.78 | PARP1 (0.72) | ALDH1A1NR4A1NR4A2NR4A3PARP1 | |
| SCHEMBL1032809 | 0.78 | SLC40A1 (0.49) | ALDH1A1NR4A1NR4A2NR4A3PARP1 | |
| SCHEMBL28798022 | 0.78 | KDM4E (0.66) | ALDH1A1LMNAKDM4EKMT2AALOX15 | |
| SCHEMBL27283354 | 0.78 | KDM4E (0.66) | ALDH1A1LMNAKDM4EKMT2AALOX15 | |
| SCHEMBL29412561 | 0.78 | PARP1 (0.72) | ALDH1A1NR4A1NR4A2NR4A3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102942524-B | Preparation method of quinoline derivative | BEIJING VAGEAN TECHNOLOGY CO LTD | 2014-12-31 | — | — | CN | disclosed |
| CN-102942524-A | Preparation method of quinoline derivative | BEIJING VAGEAN SCIENCE & TECHNOLOGY CO LTD | 2013-02-27 | — | — | CN | disclosed |