Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 12/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 10/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926571 | 1.00 | KMT2A (0.53) | KMT2ALMNAHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL11366685 | 0.86 | MAOB (0.46) | LMNAATG4BPLA2G1BMAOBTDP1 | |
| SCHEMBL8917564 | 0.85 | ALDH1A1 (0.50) | KMT2ASMN1; SMN2MAPTTHRBTDP1 | |
| SCHEMBL8917566 | 0.85 | ALDH1A1 (0.50) | KMT2ASMN1; SMN2MAPTTHRBTDP1 | |
| SCHEMBL27678556 | 0.81 | ATG4B (0.38) | KMT2ALMNAMAPTATG4BPLA2G1B | |
| SCHEMBL9696619 | 0.81 | ALDH1A1 (0.50) | ATG4BPLA2G1BMAOBTHRATHRB | |
| SCHEMBL4101066 | 0.81 | KMT2A (0.57) | KMT2ALMNAHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL15518905 | 0.81 | LMNA (0.54) | KMT2ALMNASMN1; SMN2MAPTTHRB | |
| SCHEMBL11219683 | 0.80 | LPAR2 (0.42) | LMNAMAPTMAOBTDP1ALDH1A1 | |
| SCHEMBL11219685 | 0.80 | LPAR2 (0.42) | LMNAMAPTMAOBTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103189353-A | Hydroxamate-based inhibitors of deacetylases | NOVARTIS AG | 2013-07-03 | — | — | CN | disclosed |