Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909309 | 0.86 | LMNA (0.38) | MAPTALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL27892293 | 0.84 | NPC1 (0.47) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL27790954 | 0.84 | GAA (0.51) | MAPTALDH1A1KDM4ENPC1HPGD | |
| SCHEMBL4443945 | 0.79 | CKS1B (0.47) | LGMNGPR119HDAC1HDAC2 | |
| SCHEMBL27666702 | 0.78 | GFER (0.44) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL28558686 | 0.77 | HRH3 (0.40) | GPR119GAA | |
| SCHEMBL16001294 | 0.77 | LGMN (0.58) | LGMNMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL27781993 | 0.75 | ALOX15 (0.46) | NPC1HPGDRAB9AHDAC1HDAC2 | |
| SCHEMBL26121646 | 0.74 | HPGD (0.41) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL27988992 | 0.74 | NOTUM (0.46) | MAPTALDH1A1KDM4ENPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947275-A | Piperidinyl-substituted 1, 3-dihydro-benzimidazol-2-ylideneamine derivatives | NOVARTIS AG | 2013-02-27 | — | — | CN | disclosed |