Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.40 |
| ▸ | PRKCA | P17252 | 4/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27790954 | 0.84 | GAA (0.51) | GAA | |
| SCHEMBL28552653 | 0.83 | CTSB (0.41) | HRH3GAASMOADRA1DADRA1A | |
| SCHEMBL28558248 | 0.82 | PRKCQ (0.40) | HRH3PRKCQPRKCAHTR2BGSK3B | |
| SCHEMBL27718626 | 0.81 | HTR7 (0.47) | HRH3GSK3BSMOADRA1DADRA1A | |
| SCHEMBL27643781 | 0.81 | TRPV1 (0.56) | — | |
| SCHEMBL17531192 | 0.78 | CKS1B (0.54) | — | |
| SCHEMBL27718554 | 0.78 | CHRM3 (0.38) | HRH3SMOADRA1DADRA1AADRA1B | |
| SCHEMBL27643841 | 0.77 | KDM4E (0.57) | HRH3 | |
| SCHEMBL27845996 | 0.77 | ALDH1A1 (0.56) | — | |
| SCHEMBL27909327 | 0.77 | LGMN (0.44) | GAAGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214246-A | Protein kinase C inhibitors and methods of their use | 诺华股份有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-106795151-B | Protein kinase C inhibitors and methods of their use | 诺华股份有限公司 | 2021-05-07 | — | — | CN | disclosed |