Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27706708 | 0.85 | ALDH1A1 (0.37) | MAPTALDH1A1NPC1MAPK1HTT | |
| SCHEMBL27943715 | 0.85 | KMT2A (0.51) | MAPTGAAALDH1A1NPC1MAPK1 | |
| SCHEMBL27741408 | 0.84 | ALOX15 (0.44) | MAPTALDH1A1NPC1MAPK1HTT | |
| SCHEMBL27680725 | 0.83 | CCNA2 (0.41) | CCNA2CDK2 | |
| SCHEMBL27613627 | 0.81 | ALDH1A1 (0.48) | MAPTKDM4EALDH1A1NPC1MAPK1 | |
| SCHEMBL28772407 | 0.81 | ALOX15 (0.42) | MAPTGAAHDAC1ALDH1A1NPC1 | |
| SCHEMBL3745815 | 0.81 | ALDH1A1 (0.58) | MAPTKDM4EGAAHDAC1ALDH1A1 | |
| SCHEMBL27909314 | 0.81 | MAPK1 (0.55) | MAPTGAAALDH1A1MAPK1HTT | |
| SCHEMBL28835206 | 0.80 | GPR119 (0.44) | KDM4EGAAALDH1A1ALOX15 | |
| SCHEMBL28104989 | 0.80 | GPR119 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947275-A | Piperidinyl-substituted 1, 3-dihydro-benzimidazol-2-ylideneamine derivatives | NOVARTIS AG | 2013-02-27 | — | — | CN | disclosed |