Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 6/20 | 0.38 |
| ▸ | JAK3 | P52333 | 6/20 | 0.38 |
| ▸ | JAK1 | P23458 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28104989 | 0.91 | GPR119 (0.42) | GPR119IRAK4JAK2JAK3JAK1 | |
| SCHEMBL27741408 | 0.84 | ALOX15 (0.44) | IRAK4ALOX15NOS1NOS2ALDH1A1 | |
| SCHEMBL4438915 | 0.84 | GPR119 (0.61) | GPR119IRAK4ALDH1A1 | |
| SCHEMBL28772407 | 0.81 | ALOX15 (0.42) | ALOX15ALDH1A1GAA | |
| SCHEMBL28331009 | 0.81 | GPR119 (0.37) | GPR119IRAK4ALOX15JAK2JAK3 | |
| SCHEMBL27909355 | 0.80 | MAPT (0.49) | ALOX15KDM4EALDH1A1GAA | |
| SCHEMBL7178322 | 0.80 | GPR119 (0.54) | GPR119IRAK4ALDH1A1 | |
| SCHEMBL7189717 | 0.80 | GPR119 (0.54) | GPR119IRAK4ALDH1A1 | |
| SCHEMBL7178327 | 0.80 | GPR119 (0.54) | GPR119IRAK4ALDH1A1 | |
| SCHEMBL7182896 | 0.79 | DRD2 (0.52) | GPR119IRAK4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061969-B | TRPA1 regulator | ALGOMEDIX, INC. (US) | 2019-10-29 | — | — | CN | disclosed |
| CN-106061969-A | TRPA1 modulators | 阿尔戈么迪克斯有限公司 | 2016-10-26 | — | — | CN | disclosed |