Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909451 | 0.88 | SLC27A1 (0.58) | SLC27A1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL27927214 | 0.86 | LMNA (0.52) | SLC27A1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL27927122 | 0.86 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6864740 | 0.79 | SLC27A1 (0.67) | SLC27A1SMN1; SMN2L3MBTL1NFKB1CSNK1D | |
| SCHEMBL7522067 | 0.79 | SLC27A1 (0.84) | SLC27A1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27909366 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL5327560 | 0.79 | SLC27A1 (0.66) | SLC27A1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL27909443 | 0.79 | KCNA5 (0.60) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL28804425 | 0.78 | MAPT (0.64) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL3396188 | 0.78 | SLC27A1 (0.64) | SLC27A1ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103130745-A | Diaryl-piperazines compound and medical application thereof | INST PHARM & TOXICOLOGY AMMS | 2013-06-05 | — | — | CN | claimed |
| CN-103130745-A | Diaryl-piperazines compound and medical application thereof | INST PHARM & TOXICOLOGY AMMS | 2013-06-05 | — | — | CN | disclosed |