SCHEMBL27909623

SCHEMBL27909623

O=CC1N(CCl)N=C(c2ccc(Cl)cc2)N1C1CC1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32
PDE4A P27815 1/20 0.30
GRIA1 P42261 1/20 0.30
GRIA2 P42262 1/20 0.30
GRIA3 P42263 1/20 0.30
GRIA4 P48058 1/20 0.30
GFER P55789 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27927340 0.88 L3MBTL1 (0.34) L3MBTL1
SCHEMBL27909636 0.81 TSHR (0.33) L3MBTL1
SCHEMBL27909619 0.76 ACP1 (0.31)
SCHEMBL27909625 0.75 DRD2 (0.34) L3MBTL1
SCHEMBL27927381 0.75 SLC6A4 (0.35) L3MBTL1
SCHEMBL27909621 0.74 RORC (0.33)
SCHEMBL27927316 0.73 CXCR4 (0.36)
SCHEMBL28806405 0.72 AVPR2 (0.36)
SCHEMBL27909620 0.72 TACR2 (0.35) PDE4A
SCHEMBL27770358 0.69 PDE4A (0.32) PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103189363-B Biaryl linked aryl triazolones and uses thereof BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-07-29 CN disclosed
CN-103189363-A Biaryl linked aryl triazolones and uses thereof BAYER IP GMBH 2013-07-03 CN disclosed