Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770365 | 0.81 | ALDH1A1 (0.35) | MEN1KMT2ANPSR1 | |
| SCHEMBL27749306 | 0.78 | PTPN11 (0.37) | — | |
| SCHEMBL27770364 | 0.75 | RXFP1 (0.39) | MEN1KMT2A | |
| SCHEMBL27770354 | 0.73 | GAA (0.39) | MEN1KMT2ANPSR1 | |
| SCHEMBL28781522 | 0.72 | GABRA1 (0.32) | PDE4AMEN1KMT2ANPSR1 | |
| SCHEMBL27909623 | 0.69 | L3MBTL1 (0.32) | PDE4A | |
| SCHEMBL28058456 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL28058452 | 0.66 | ALDH1A1 (0.31) | — | |
| SCHEMBL28058563 | 0.65 | MAOA (0.32) | KMT2A | |
| SCHEMBL28058503 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103189363-B | Biaryl linked aryl triazolones and uses thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-07-29 | — | — | CN | disclosed |
| CN-101495458-B | Substituted arylimidazolone and triazolone as inhibitors of vasopressin receptors | BAYER IP GMBH | 2014-01-29 | — | — | CN | disclosed |
| CN-103189363-A | Biaryl linked aryl triazolones and uses thereof | BAYER IP GMBH | 2013-07-03 | — | — | CN | disclosed |
| CN-101495458-A | Substituted arylimidazolone and triazolone as inhibitors of vasopressin receptors | BAYER HEALTHCARE AG (DE) | 2009-07-29 | — | — | CN | disclosed |