SCHEMBL27909665

SCHEMBL27909665

CC(C)c1cc(CC(OC=O)c2ccc(Cl)cc2Cl)n[nH]1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.35
TP53 P04637 3/20 0.35
HTT P42858 1/20 0.35
POLB P06746 1/20 0.33
CYP2C9 P11712 6/20 0.32
CYP3A4 P08684 4/20 0.32
IDO1 P14902 4/20 0.32
CYP1A2 P05177 3/20 0.32
CYP2D6 P10635 3/20 0.32
CYP2C19 P33261 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPT P10636 2/20 0.32
ALPL P05186 2/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
RAF1 P04049 1/20 0.31
ULK1 O75385 1/20 0.31
CYP19A1 P11511 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27935383 0.83 IDO1 (0.34) LMNATP53HTTPOLBCYP2C9
SCHEMBL27892597 0.80 MAPT (0.37) LMNAPOLBIDO1MEN1KMT2A
SCHEMBL27909617 0.72 LMNA (0.33) LMNAPOLBCYP2C9CYP3A4IDO1
SCHEMBL28272803 0.71 CYP1A2 (0.31) CYP2C9CYP3A4CYP1A2CYP2D6CYP2C19
SCHEMBL5536369 0.68 IDO1 (0.47) LMNATP53HTTPOLBCYP3A4
SCHEMBL10249053 0.66 TP53 (0.45) LMNATP53POLBMAPTRAF1
SCHEMBL30439455 0.66 HCAR3 (0.47) LMNATP53HTTMEN1KMT2A
SCHEMBL28786429 0.65 NOTUM (0.36) LMNAIDO1MEN1KMT2AMAPT
SCHEMBL1206441 0.65 HCAR2 (0.44) TP53MAPTTSHRMAPK1
SCHEMBL28089341 0.64 HCAR2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104270946-A Use of anthranilic acid diamide derivatives for controlling pests in transgenic crops BAYER CROPSCIENCE AG 2015-01-07 CN disclosed
CN-103155916-A Selective Insecticides Based on Anthranilic Acid Diamides and Safeners BAYER CROPSCIENCE AG 2013-06-19 CN disclosed
CN-101331878-B Selective insecticides based on anthranilic acid diamides and safeners BAYER CROPSCIENCE AG 2013-03-06 CN disclosed