SCHEMBL28272803

SCHEMBL28272803

O=COC(Cc1cc(O)[nH]n1)c1ccccc1Cl

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CTSA P10619 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27892597 0.74 MAPT (0.37) CTSA
SCHEMBL28113598 0.73 CTSK (0.34) CYP1A2
SCHEMBL28113601 0.72 XPO1 (0.35) CYP2D6CYP2C9CYP2C19
SCHEMBL27909665 0.71 LMNA (0.35) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL28325986 0.70 HCAR3 (0.34)
SCHEMBL27935383 0.70 IDO1 (0.34) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL27627222 0.70 HCAR3 (0.30)
SCHEMBL28805211 0.69 ROCK2 (0.31)
SCHEMBL28113602 0.68
SCHEMBL27944384 0.67 GLS (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109152368-A Substituted sulfonamides for combating animal pests 拜耳作物科学股份公司 2019-01-04 CN disclosed