Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27946397 | 0.88 | NPC1 (0.50) | CTRB1LMNAHPGDHPGDSNPC1 | |
| SCHEMBL5134568 | 0.81 | CTRB1 (0.56) | CTRB1LMNAHPGDHPGDSNPC1 | |
| SCHEMBL6398252 | 0.81 | CYP2D6 (0.44) | CTRB1LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL15079019 | 0.79 | CTRB1 (0.56) | CTRB1LMNAHPGDHPGDSNPC1 | |
| SCHEMBL4458404 | 0.79 | HPGDS (0.79) | CTRB1LMNAHPGDHPGDSALDH1A1 | |
| SCHEMBL22534206 | 0.79 | CNR2 (0.63) | CTRB1LMNAHPGDHPGDSNPC1 | |
| SCHEMBL27693084 | 0.78 | SLC1A2 (0.55) | CTRB1LMNAHPGDHPGDSNPC1 | |
| SCHEMBL27825223 | 0.78 | ALDH1A1 (0.54) | CTRB1LMNAHPGDNPC1ALDH1A1 | |
| SCHEMBL28743856 | 0.78 | GAA (0.54) | CTRB1LMNAALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL4670025 | 0.78 | CTRB1 (0.62) | CTRB1LMNAHPGDHPGDSNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102964195-B | Method for preparing second-level and third-level substituted amide | UNIV WENZHOU | 2015-06-24 | — | — | CN | disclosed |
| CN-102964195-A | Method for preparing second-level and third-level substituted amide | UNIV WENZHOU | 2013-03-13 | — | — | CN | disclosed |