Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 6/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28983041 | 0.83 | CTRB1 (0.53) | CTRB1HDAC3CA12CA1IDO1 | |
| SCHEMBL27825223 | 0.83 | ALDH1A1 (0.54) | CTRB1HDAC3CA12CA1IDO1 | |
| SCHEMBL27693084 | 0.83 | SLC1A2 (0.55) | CTRB1HDAC3CA12CA1IDO1 | |
| SCHEMBL28641833 | 0.81 | HDAC3 (0.58) | CTRB1HDAC3CA12CA1IDO1 | |
| SCHEMBL27909776 | 0.81 | CTRB1 (0.61) | CTRB1HDAC3CA12CA1IDO1 | |
| SCHEMBL8815154 | 0.79 | CTRB1 (0.50) | CTRB1HDAC3CA12CA1IDO1 | |
| SCHEMBL28118956 | 0.79 | HDAC3 (0.56) | CTRB1HDAC3CA12CA1IDO1 | |
| SCHEMBL2132047 | 0.78 | HPGD (0.50) | CTRB1HDAC3CA12CA1IDO1 | |
| SCHEMBL16094230 | 0.78 | ALDH1A1 (0.59) | CA1CA9LMNAHPGDGAA | |
| SCHEMBL4882314 | 0.78 | CTRB1 (0.49) | CTRB1HDAC3CA12CA1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890691-A1 | BENZIMIDAZOLE DERIVATIVES AS ITK INHIBITORS | Principia Biopharma Inc. (US) | 2015-07-08 | — | — | EP | claimed |
| WO-2014036016-A1 | BENZIMIDAZOLE DERIVATIVES AS ITK INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2014-03-06 | — | — | WO | claimed |
| CN-1791569-A | Difluoromethylbenzanilides and use thereof for combating micro-organisms, intermediate products and use thereof | BAYER CROPSCIENCE AG (DE) | 2006-06-21 | — | — | CN | claimed |
| WO-2025132758-A1 | PESTICIDALLY ACTIVE QUINAZOLINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-06-26 | — | — | WO | disclosed |
| CN-106661035-B | The Pyrazolopyrimidine derivative of inhibitor as bruton's tyrosine kinase | 洛克索肿瘤学股份有限公司 | 2019-11-19 | — | — | CN | disclosed |
| CN-109641854-A | Integration stress access regulator | 卡里科生命科学有限责任公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-102119143-B | Amide derivative, pest control agent containing the same, and method of using the pest control agent | 三井化学AGRO株式会社 | 2017-07-21 | — | — | CN | disclosed |
| CN-106661035-A | Pyrazolopyrimidine derivatives as inhibitors of bruton's tyrosine kinase | 莱德克斯制药公共有限公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-3148975-A1 | NOVEL COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2017-04-05 | — | — | EP | disclosed |
| CN-106536489-A | Novel compounds | 葛兰素史密斯克莱知识产权发展有限公司 | 2017-03-22 | — | — | CN | disclosed |
| WO-2015180612-A1 | NOVEL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-12-03 | — | — | WO | disclosed |
| CN-102341394-B | Poly (ADP-Ribose) Polymerase (PARP) Inhibitors | TAKEDA PHARMACEUTICAL | 2015-04-15 | — | — | CN | disclosed |
| EP-2718279-A1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | Rhizen Pharmaceuticals S.A. (CH) | 2014-04-16 | — | — | EP | disclosed |
| WO-2014036016-A1 | BENZIMIDAZOLE DERIVATIVES AS ITK INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2014-03-06 | — | — | WO | disclosed |
| WO-2012170867-A1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | RHIZEN PHARMACEUTICALS SA (CH) | 2012-12-13 | — | — | WO | disclosed |
| US-8252831-B2 | Imidazole-2-benzamide compounds useful for the treatment of osteoarthritis | ELI LILLY AND COMPANY (US) | 2012-08-28 | — | — | US | disclosed |
| US-20120157506-A1 | Novel Imidazole-2-Benzamide Compounds Useful for the Treatment of Osteoarthritis | ELI LILLY AND COMPANY (US) | 2012-06-21 | — | — | US | disclosed |
| EP-1960350-A1 | NEW N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007060162-A1 | NEW N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2007-05-31 | — | — | WO | disclosed |
| CN-1791569-A | Difluoromethylbenzanilides and use thereof for combating micro-organisms, intermediate products and use thereof | BAYER CROPSCIENCE AG (DE) | 2006-06-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157506-A1 | Novel Imidazole-2-Benzamide Compounds Useful for the Treatment of Osteoarthritis | ARG2, HDAC6, COL2A1 | CTRB1 3348/4885HDAC3 11/4885CA12 3462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.