Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27930077 | 0.85 | GSTO1 (0.40) | GSTO1MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL160421 | 0.77 | NR1H4 (0.50) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL28805064 | 0.72 | ERCC5 (0.33) | LTB4RERCC5FEN1USP30 | |
| SCHEMBL14409853 | 0.72 | KMT2A (0.50) | GSTO1MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL27930202 | 0.72 | OPRM1 (0.35) | SMN1; SMN2ERCC5FEN1USP30 | |
| SCHEMBL27930057 | 0.71 | HDAC6 (0.34) | ERCC5FEN1USP30 | |
| SCHEMBL162321 | 0.70 | NR1H4 (0.48) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL162514 | 0.69 | DGAT1 (0.48) | SMN1; SMN2 | |
| SCHEMBL6229570 | 0.69 | RAB9A (0.51) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL163110 | 0.68 | ERCC5 (0.36) | LTB4RERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103228633-A | Heterocyclic compounds as DGAT1 inhibitors | PIRAMAL LIFE SCIENCES LTD | 2013-07-31 | — | — | CN | disclosed |