Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170720 | 0.97 | TP53 (0.50) | TP53CALM1TSHRALDH1A1IDO1 | |
| SCHEMBL2032974 | 0.81 | CALM1 (0.50) | TP53CALM1TSHRALDH1A1IDO1 | |
| SCHEMBL19809460 | 0.78 | TP53 (0.46) | TP53CALM1TSHRALDH1A1IDO1 | |
| Fluoride SCHEMBL27912810 | 0.78 | TP53 (0.41) | TP53MAPK1 | |
| Fluoride SCHEMBL27912809 | 0.78 | TP53 (0.41) | TP53MAPK1 | |
| SCHEMBL27595305 | 0.75 | TP53 (0.42) | TP53MAPK1 | |
| Fluoride SCHEMBL27931074 | 0.74 | TP53 (0.46) | TP53CALM1TSHRALDH1A1IDO1 | |
| SCHEMBL8575149 | 0.73 | TP53 (0.46) | TP53ALDH1A1LOXL2TDP1CYP3A4 | |
| SCHEMBL22050864 | 0.73 | TP53 (0.41) | TP53CALM1TSHRALDH1A1 | |
| SCHEMBL6268172 | 0.73 | SIGMAR1 (0.44) | TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103249762-A | Addition-curable metallosiloxane compound | DAICEL CORP | 2013-08-14 | — | — | CN | disclosed |