Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL27912810 | 1.00 | TP53 (0.41) | TP53SMN1; SMN2SIGMAR1DNM1MEN1 | |
| SCHEMBL27595305 | 0.98 | TP53 (0.42) | TP53SMN1; SMN2SIGMAR1DNM1MEN1 | |
| SCHEMBL6268172 | 0.92 | SIGMAR1 (0.44) | TP53SMN1; SMN2SIGMAR1DNM1MEN1 | |
| SCHEMBL28520856 | 0.90 | DNM1 (0.46) | TP53SMN1; SMN2SIGMAR1DNM1MEN1 | |
| SCHEMBL19809460 | 0.85 | TP53 (0.46) | TP53SMN1; SMN2SIGMAR1 | |
| SCHEMBL5681515 | 0.80 | MAOA (0.54) | SMN1; SMN2SIGMAR1 | |
| SCHEMBL8389964 | 0.79 | SIGMAR1 (0.48) | TP53SMN1; SMN2SIGMAR1KCNH2 | |
| SCHEMBL23532541 | 0.78 | MAOA (0.52) | SMN1; SMN2SIGMAR1MAPK1 | |
| Fluoride SCHEMBL27912944 | 0.78 | TP53 (0.48) | TP53MAPK1 | |
| SCHEMBL7170720 | 0.75 | TP53 (0.50) | TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103249762-A | Addition-curable metallosiloxane compound | DAICEL CORP | 2013-08-14 | — | — | CN | disclosed |