Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.38 |
| ▸ | PNMT | P11086 | 2/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid Methyl Ester SCHEMBL28702515 | 0.80 | MAPT (0.42) | TDP1MAPTPOLBHSD17B3PNMT | |
| Ethoxycarbonyl Group SCHEMBL27497693 | 0.80 | TSHR (0.44) | TDP1MAPTPOLBRAB9ANPC1 | |
| Ethoxycarbonyl Group SCHEMBL28070920 | 0.78 | NLRP3 (0.37) | TDP1MAPTPOLBRAB9ANPC1 | |
| SCHEMBL1468326 | 0.77 | PNMT (0.54) | TDP1MAPTHSD17B3PNMTASIC3 | |
| Ethoxycarbonyl Group SCHEMBL27738688 | 0.76 | MAPT (0.43) | MAPTHSD17B3RAB9ANPC1CYP1A2 | |
| SCHEMBL7854686 | 0.76 | HSD17B3 (0.40) | HSD17B3PNMTASIC3ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL28759209 | 0.75 | PNMT (0.52) | TDP1MAPTHSD17B3PNMTASIC3 | |
| Ammonia Solution, Strong SCHEMBL4733194 | 0.75 | PNMT (0.52) | TDP1MAPTHSD17B3PNMTASIC3 | |
| SCHEMBL30406919 | 0.73 | PNMT (0.54) | TDP1MAPTHSD17B3PNMTASIC3 | |
| SCHEMBL749569 | 0.73 | PNMT (0.54) | TDP1MAPTHSD17B3PNMTASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103189361-A | Estrogen receptor modulators and use thereof | ARAGON PHARMACEUTICALS INC | 2013-07-03 | — | — | CN | disclosed |