Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27497693 | 0.79 | TSHR (0.44) | POLBRAB9ANPC1CASP3SENP8 | |
| Ethoxycarbonyl Group SCHEMBL27913073 | 0.78 | TDP1 (0.39) | POLBRAB9ANPC1CASP3ATM | |
| Ethoxycarbonyl Group SCHEMBL28070924 | 0.77 | KDM4E (0.33) | MEN1KMT2AMAPTHPGDKDM4E | |
| Ethoxycarbonyl Group SCHEMBL27767789 | 0.76 | TRIM24 (0.35) | MEN1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL3208997 | 0.74 | POLB (0.42) | POLBRAB9ANPC1MEN1KMT2A | |
| Ethoxycarbonyl Group SCHEMBL28100826 | 0.74 | — | — | |
| Cyclopentane SCHEMBL28273622 | 0.72 | ALDH1A1 (0.32) | TDP1ALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL27496535 | 0.72 | — | — | |
| Cyclopentane SCHEMBL8158405 | 0.72 | ALDH1A1 (0.32) | TDP1ALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL27739080 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814062-A | Spiro-oxazolones | 豪夫迈·罗氏有限公司 | 2016-07-27 | — | — | CN | disclosed |