Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 2/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1468326 | 0.81 | PNMT (0.54) | HSD17B3PNMTASIC3ADRA2AADRA2B | |
| SCHEMBL7861297 | 0.79 | EGFR (0.43) | ADRA2ANPC1RAB9ANAMPTALDH1A1 | |
| SCHEMBL7861344 | 0.79 | DRD2 (0.40) | NPC1RAB9ACYP1A2CYP2D6HPGD | |
| Hydrochloric Acid SCHEMBL28759209 | 0.79 | PNMT (0.52) | HSD17B3PNMTASIC3ADRA2AADRA2B | |
| Ammonia Solution, Strong SCHEMBL4733194 | 0.79 | PNMT (0.52) | HSD17B3PNMTASIC3ADRA2AADRA2B | |
| SCHEMBL7854631 | 0.77 | MLNR (0.52) | CYP2D6ALDH1A1HTR2CHTR2B | |
| SCHEMBL7862501 | 0.77 | NPC1 (0.41) | ADRA2ANPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL7861299 | 0.77 | NPC1 (0.44) | ADRA2ANPC1RAB9ANAMPTCYP1A2 | |
| SCHEMBL7862464 | 0.77 | TPSAB1 (0.47) | ADRA2ANPC1RAB9ANAMPTSMN1; SMN2 | |
| SCHEMBL30406919 | 0.77 | PNMT (0.54) | HSD17B3PNMTASIC3ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807101-B1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | UPJOHN CO (US) | 2001-06-13 | — | — | EP | disclosed |
| US-5936000-A | 2-aminoindans as selective dopamine D3 ligands | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0807101-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023760-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |