Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.67 |
| ▸ | RAB9A | P51151 | 8/20 | 0.67 |
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.67 |
| ▸ | RELA | Q04206 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.67 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.67 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11887737 | 0.80 | NPC1 (1.00) | GAAPOLBSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL10596351 | 0.76 | RAB9A (0.82) | POLBSMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL25155011 | 0.73 | LMNA (1.00) | POLBSMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL14096559 | 0.72 | NPC1 (1.00) | GAAPOLBSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL4250099 | 0.72 | MAPT (0.70) | POLBSMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL4252995 | 0.72 | LMNA (0.70) | POLBSMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL3503703 | 0.71 | NPC1 (0.73) | POLBSMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL19771114 | 0.70 | POLB (0.74) | POLBSMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL4246439 | 0.69 | SMN1; SMN2 (0.64) | GAASMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL6848441 | 0.69 | NPC1 (0.76) | GAAPOLBSMN1; SMN2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102994611-A | Establishing method for drug screening model of high-throughput Japanese encephalitis virus helicase inhibitor | UNIV HUAZHONG AGRICULTURAL | 2013-03-27 | — | — | CN | disclosed |