SCHEMBL7208250

SCHEMBL7208250

CCCCc1ccc(N(c2ccc(C)c(C)c2)c2ccc(-c3ccc(N(c4ccc(CCCC)cc4)c4ccc(C)c(C)c4)c(C)c3)cc2C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.42
SKP2 Q13309 1/20 0.39
HSD11B1 P28845 2/20 0.38
CYP3A4 P08684 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C9 P11712 2/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
NISCH Q9Y2I1 1/20 0.37
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
CYP4Z1 Q86W10 1/20 0.35
CYP4F11 Q9HBI6 1/20 0.35
CYP4F12 Q9HCS2 1/20 0.35
RARA P10276 1/20 0.34
RARG P13631 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19346857 0.95 HSD11B1 (0.43) RARBSKP2HSD11B1CYP3A4CYP2D6
SCHEMBL11887126 0.93 RARB (0.47) RARBSKP2HSD11B1CYP3A4CYP2D6
SCHEMBL11887135 0.92 MCL1 (0.38) RARBNISCHNPC1TP53RAB9A
SCHEMBL12316360 0.89 RARB (0.35) RARB
SCHEMBL279458 0.89 RARB (0.38) RARBCYP3A4CYP2D6CYP2C9CA2
SCHEMBL11887117 0.89 RARB (0.53) RARBHSD11B1CYP3A4ALDH1A1HPGD
SCHEMBL13681228 0.87 RARB (0.34) RARB
SCHEMBL2260320 0.87 RARB (0.45) RARBSKP2HSD11B1CYP3A4CYP2D6
SCHEMBL11887124 0.87 RARB (0.45) RARBSKP2HSD11B1CYP3A4CYP2D6
SCHEMBL438986 0.86 S1PR1 (0.37) RARBCA2ALDH1A1RARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7324059-A None JP disclosed
US-20170263884-A1 ORGANIC LIGHT-EMITTING DIODE DISPLAY PANEL, FABRICATION METHOD, AND ELECTRONIC APPARATUS WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2017-09-14 US disclosed
US-20170263884-A1 ORGANIC LIGHT-EMITTING DIODE DISPLAY PANEL, FABRICATION METHOD, AND ELECTRONIC APPARATUS WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2017-09-14 US disclosed
US-20120189948-A1 CHARGE TRANSPORT FILM, ORGANIC ELECTRONIC DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2012-07-26 US disclosed
US-20120189948-A1 CHARGE TRANSPORT FILM, ORGANIC ELECTRONIC DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2012-07-26 US disclosed
EP-1095931-B1 Benzidine derivatives and electrophotosensitive material using the same KYOCERA MITA CORP (JP) 2003-02-05 EP disclosed
EP-0799818-B1 Benzidine derivatives and electrophotosensitive material using the same KYOCERA MITA CORP (JP) 2002-05-02 EP disclosed
EP-1095931-A1 Benzidine derivatives and electrophotosensitive material using the same KYOCERA MITA CORPORATION (JP) 2001-05-02 EP disclosed
EP-0648737-B1 Benzidine derivatives and electrophotosensitive material using the same MITA INDUSTRIAL CO LTD (JP) 1998-07-15 EP disclosed
EP-0799818-A2 Benzidine derivatives and electrophotosensitive material using the same MITA INDUSTRIAL CO. LTD. (JP) 1997-10-08 EP disclosed
US-5550290-A CHARGE TRANSFER COMPOUND MITA INDUSTRIAL CO. LTD. (JP) 1996-08-27 US disclosed
JP-H07324059-A BENZIDINE DERIVATIVE AND ELECTROPHOTOGRAPHIC SENSITIZER USING THE SAME MITA IND CO LTD 1995-12-12 JP disclosed
EP-0648737-A1 Benzidine derivatives and electrophotosensitive material using the same MITA INDUSTRIAL CO. LTD. (JP) 1995-04-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170263884-A1 ORGANIC LIGHT-EMITTING DIODE DISPLAY PANEL, FABRICATION METHOD, AND ELECTRONIC APPARATUS OCIAD1, OCIAD2, OPRD1 RARB 2387/4885SKP2 1440/4885HSD11B1 1831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.