Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1004651 | 0.90 | RXRA (0.47) | RXRARXRBTSHRLMNAHTT | |
| SCHEMBL7902893 | 0.86 | TSHR (0.47) | RXRARXRBTSHRLMNAHTT | |
| SCHEMBL17382019 | 0.81 | ADRA1D (0.49) | RXRARXRBTSHRLMNAHTT | |
| SCHEMBL13870393 | 0.81 | RXRA (0.41) | RXRARXRBTSHRLMNAHTT | |
| SCHEMBL4515297 | 0.78 | PARP10 (0.47) | RXRARXRBTSHRLMNAHTT | |
| SCHEMBL608037 | 0.78 | PTGS2 (0.39) | RXRARXRBTSHRPTGS2GAA | |
| SCHEMBL22096779 | 0.77 | TSHR (0.41) | RXRARXRBTSHRLMNAHTT | |
| SCHEMBL9970966 | 0.77 | PARP1 (0.46) | RXRARXRBTSHRLMNAHTT | |
| SCHEMBL27915060 | 0.76 | CHEK2 (0.45) | LMNAGAAALDH1A1MAPTKDM4E | |
| SCHEMBL12075502 | 0.75 | GPR84 (0.41) | RXRARXRBTSHRPTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261156-A | New compounds for the treatment of neurodegenerative diseases | LEUVEN K U RES & DEV | 2013-08-21 | — | — | CN | disclosed |