Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15127544 | 0.83 | ACHE (0.49) | GAACHRM3CHRM1KMT2ACHRM2 | |
| SCHEMBL3635381 | 0.80 | L3MBTL3 (0.46) | CHRM3CHRM1MEN1KMT2ACHRM2 | |
| SCHEMBL16209901 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL3652874 | 0.74 | CYP2D6 (0.48) | SMN1; SMN2GAACHRM3CHRM1KMT2A | |
| SCHEMBL9967818 | 0.74 | CHRM3 (0.45) | SMN1; SMN2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL16209989 | 0.71 | SMN1; SMN2 (0.40) | SMN1; SMN2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL16209793 | 0.71 | CHRM3 (0.64) | CHRM3CHRM1CHRM2 | |
| SCHEMBL6763904 | 0.70 | CES1 (0.47) | SMN1; SMN2GAACHRM3CHRM1CHRM2 | |
| SCHEMBL4009225 | 0.69 | KCNN4 (0.55) | SMN1; SMN2GAACHRM3CHRM1MEN1 | |
| SCHEMBL4894399 | 0.69 | CHRM3 (0.73) | CHRM3CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101663270-B | Quaternary ammonium compounds useful as muscarinic receptor antagonists | THERAVANCE INC | 2013-07-17 | — | — | CN | disclosed |