Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27591140 | 0.90 | ALDH1A1 (0.37) | ALDH1A1PKMLMNASMN1; SMN2TDP1 | |
| SCHEMBL27591138 | 0.80 | — | — | |
| SCHEMBL27572608 | 0.78 | CA1 (0.46) | LMNA | |
| SCHEMBL27915239 | 0.74 | KDM4E (0.33) | PKMSMN1; SMN2 | |
| SCHEMBL589219 | 0.72 | ALDH1A1 (0.61) | ALDH1A1PKMHTTLMNAMEN1 | |
| SCHEMBL27979918 | 0.69 | TLR9 (0.36) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7107937 | 0.69 | TLR9 (0.39) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27691091 | 0.68 | PKM (0.33) | ALDH1A1PKMHTTLMNAMEN1 | |
| SCHEMBL27592268 | 0.67 | TLR9 (0.38) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28783948 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101594862-B | Substituted indazole derivatives as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-11-25 | — | — | CN | disclosed |