SCHEMBL27916248

SCHEMBL27916248

COc1ccc2c(=O)c(-c3ccc(OC)c(O)c3O)coc2c1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.80
MAPT P10636 9/20 0.80
ALDH1A1 P00352 7/20 0.80
HPGD P15428 6/20 0.80
HSD17B10 Q99714 6/20 0.80
ALOX15 P16050 2/20 0.80
RECQL P46063 1/20 0.80
TDP1 Q9NUW8 1/20 0.80
CYP3A4 P08684 5/20 0.70
RAB9A P51151 7/20 0.66
NPC1 O15118 6/20 0.66
XDH P47989 1/20 0.64
SMN1; SMN2 Q16637 7/20 0.63
TP53 P04637 4/20 0.63
MEN1 O00255 3/20 0.63
KMT2A Q03164 3/20 0.63
MAOA P21397 2/20 0.57
MAOB P27338 2/20 0.57
USP2 O75604 1/20 0.57
GLA P06280 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Koparin SCHEMBL29477154 0.89 KDM4E (1.00) KDM4EMAPTALDH1A1HPGDHSD17B10
Koparin SCHEMBL5723673 0.89 KDM4E (1.00) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL5241998 0.85 MAPT (0.74) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL7054594 0.85 KDM4E (0.83) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL2971118 0.85 XDH (0.76) KDM4EMAPTALDH1A1HPGDHSD17B10
2'-Methoxyformonetin SCHEMBL29777010 0.82 KDM4E (1.00) KDM4EMAPTALDH1A1HPGDHSD17B10
2'-Methoxyformonetin SCHEMBL234355 0.82 KDM4E (1.00) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL4832045 0.82 RAB9A (0.72) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL1249332 0.81 ALDH1A1 (0.71) KDM4EMAPTALDH1A1HPGDHSD17B10
Xenognosin B SCHEMBL72611 0.81 KDM4E (0.83) KDM4EMAPTALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116898933-A Traditional Chinese medicine composition for treating ulcerative colitis and preparation method thereof 吉林农业科技学院 2023-10-20 CN disclosed
CN-114949091-A Traditional Chinese medicine formula for treating female pathological and climacteric dryness and astringency syndrome 张凤霞 2022-08-30 CN disclosed
CN-106389788-B It is a kind of for enhancing the drug extract, preparation and preparation method of immunologic function of livestock and birds and anti-virus ability 青岛农业大学 2019-09-13 CN disclosed
CN-109771567-A A kind of formula of Chinese herbal medicine supporting vital QI and dispersing blood stasis toxin expelling tumour 严跃华 2019-05-21 CN disclosed
CN-109646498-A For treating the Chinese medicine composition of ankylosing spondylitis 吴蓓莉 2019-04-19 CN disclosed
CN-109453274-A It is a kind of for treating the Chinese medicine composition of myasthenia gravis 吴蓓莉 2019-03-12 CN disclosed
CN-109331100-A It is a kind of for treating the Chinese medicine composition of cerebral infarction sequelae 史利 2019-02-15 CN disclosed
CN-109260349-A It is a kind of for treating the Chinese medicine composition of breast cancer 史利 2019-01-25 CN disclosed
CN-109248297-A It is a kind of for treating the Chinese medicine composition of lung cancer 史利 2019-01-22 CN disclosed
CN-109248278-A It is a kind of for treating the Chinese medicine composition of nasopharyngeal carcinoma 史利 2019-01-22 CN disclosed
CN-105454576-A Jasmine-flower-comprising assorted Chinese herbal tea and preparation method thereof CHEN YANYING 2016-04-06 CN disclosed
CN-103969354-B A kind of discrimination method of finger-print of Shengkang injection solution (for nephrosis) Xi'an Shijishengkang Pharmaceutical Industry Co., Ltd. (CN) 2016-01-13 CN disclosed
CN-104605439-A Mulberry and sharpleaf galangal fruit beverage and preparation method thereof UNIV GUIZHOU NORMAL 2015-05-13 CN disclosed
CN-104569199-A Measuring method for astragalus membranaceus fingerprint spectrum SHANGHAI SUNDISE TRADITIONAL CHINESE MEDICINE CO LTD 2015-04-29 CN disclosed
CN-103536697-B Nutrient solution for improving fertilization rate of artificial insemination of poultry QIYANG GAODE PLANTING AND BREEDING SPECIALIZED COOPERATIVES 2015-02-25 CN disclosed
CN-103969354-A Identification method for fingerprint spectrum of Shenkang injection XI AN SHIJISHENGKANG PHARMACEUTICAL INDUSTRY CO LTD 2014-08-06 CN disclosed
CN-103969382-A Identification method for fingerprint spectrum of safflower-astragalus extract XI AN SHIJISHENGKANG PHARMACEUTICAL INDUSTRY CO LTD 2014-08-06 CN disclosed
CN-103969355-A Identification method for fingerprint spectrum of astragalus medicinal material XI AN SHIJISHENGKANG PHARMACEUTICAL INDUSTRY CO LTD 2014-08-06 CN disclosed
CN-103536697-A Nutrient solution for improving fertilization rate of artificial insemination of poultry QIYANG GAODE PLANTING AND BREEDING SPECIALIZED COOPERATIVES 2014-01-29 CN disclosed
CN-103239499-A Medicine for treating cardiovascular and cerebrovascular diseases and preparation method thereof ZHU YUYING 2013-08-14 CN disclosed