Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676909 | 0.93 | KMT2A (0.58) | MMP2MMP9MMP14ELANEKMT2A | |
| SCHEMBL545687 | 0.92 | HPGD (0.58) | MMP2MMP9MMP14HPGDSMN1; SMN2 | |
| SCHEMBL21991485 | 0.90 | MMP2 (0.49) | MMP2MMP9MMP14ELANEKMT2A | |
| SCHEMBL8779173 | 0.86 | KMT2A (0.52) | MMP2MMP9MMP14ELANEKMT2A | |
| SCHEMBL697317 | 0.86 | CA1 (0.56) | KMT2AMEN1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL21991789 | 0.85 | KIF11 (0.51) | MMP2MMP9MMP14ELANEKMT2A | |
| SCHEMBL1598492 | 0.84 | LMNA (0.61) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL8830906 | 0.84 | KMT2A (0.50) | MMP2MMP9MMP14ELANEKMT2A | |
| SCHEMBL24419014 | 0.82 | KMT2A (0.52) | MMP2MMP9MMP14KMT2AMEN1 | |
| SCHEMBL6937289 | 0.82 | KMT2A (0.48) | MMP2MMP9MMP14ELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |