Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.58 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918218 | 0.91 | KLKB1 (0.56) | NPC1RAB9ASMN1; SMN2MAPTMAOB | |
| SCHEMBL27936605 | 0.88 | MAOB (0.65) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27918087 | 0.88 | MAOB (0.65) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27936544 | 0.86 | MAPT (0.60) | NPC1RAB9AALDH1A1MAPTPKM | |
| SCHEMBL27936581 | 0.84 | KLKB1 (0.78) | KLKB1MET | |
| SCHEMBL11690669 | 0.82 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27936600 | 0.81 | APP (0.53) | ALDH1A1MAOBMEN1KMT2ATP53 | |
| SCHEMBL8062716 | 0.80 | MAOB (0.69) | MAOBMEN1KMT2ALMNA | |
| SCHEMBL10132123 | 0.79 | MEN1 (0.69) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3214018 | 0.78 | MAOB (0.63) | NPC1RAB9ASMN1; SMN2MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | claimed |
| CN-103304438-B | N-substituted salicylamide compounds, preparation method and application | SHANDONG UNIVERSITY (CN) | 2015-12-02 | — | — | CN | disclosed |
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | disclosed |