Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.65 |
| ▸ | MAOA | P21397 | 6/20 | 0.65 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918216 | 0.88 | NPC1 (0.62) | MAOBKLKB1NPC1MAPTRAB9A | |
| SCHEMBL27936605 | 0.88 | MAOB (0.65) | MAOBMAOAKLKB1NPC1MAPT | |
| SCHEMBL27936544 | 0.85 | MAPT (0.60) | MAOBMAOAKLKB1NPC1MAPT | |
| SCHEMBL27936581 | 0.82 | KLKB1 (0.78) | KLKB1MET | |
| SCHEMBL27918218 | 0.81 | KLKB1 (0.56) | MAOBKLKB1NPC1MAPTRAB9A | |
| SCHEMBL3302570 | 0.80 | MAOB (0.73) | MAOBMAOAPARP15PARP10NPC1 | |
| SCHEMBL13298042 | 0.80 | MAOB (0.77) | MAOBMAOAPARP15PARP10NPC1 | |
| SCHEMBL27918116 | 0.76 | FADS1 (0.65) | MAOBMAOAKLKB1NPC1MAPT | |
| SCHEMBL3301580 | 0.76 | MAOB (0.78) | MAOBMAOAPARP15PARP10PARP14 | |
| SCHEMBL31580963 | 0.74 | MAOB (0.77) | MAOBMAOAPARP15PARP10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | claimed |
| CN-103304438-B | N-substituted salicylamide compounds, preparation method and application | SHANDONG UNIVERSITY (CN) | 2015-12-02 | — | — | CN | disclosed |
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | disclosed |