Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.56 |
| ▸ | MET | P08581 | 2/20 | 0.55 |
| ▸ | PLAU | P00749 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | PLAT | P00750 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918216 | 0.91 | NPC1 (0.62) | KLKB1METMEN1KMT2ANPC1 | |
| SCHEMBL27918116 | 0.87 | FADS1 (0.65) | KLKB1METMEN1KMT2ANPC1 | |
| SCHEMBL27936581 | 0.85 | KLKB1 (0.78) | KLKB1METPLAUF2F10 | |
| SCHEMBL27936600 | 0.82 | APP (0.53) | MEN1KMT2ATP53MAOBHPGD | |
| SCHEMBL3297118 | 0.82 | PPARD (0.54) | NPC1RAB9AMAPK1MAOBHPGD | |
| SCHEMBL3210641 | 0.82 | MAOB (0.65) | MAPK1MAOBHPGDPPARD | |
| SCHEMBL27936605 | 0.81 | MAOB (0.65) | KLKB1METNPC1RAB9ATP53 | |
| SCHEMBL27918087 | 0.81 | MAOB (0.65) | KLKB1METMEN1KMT2ANPC1 | |
| SCHEMBL10476884 | 0.81 | LMNA (0.69) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL13812749 | 0.81 | MET (0.60) | KLKB1METMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | claimed |
| CN-103304438-B | N-substituted salicylamide compounds, preparation method and application | SHANDONG UNIVERSITY (CN) | 2015-12-02 | — | — | CN | disclosed |
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | disclosed |