Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.65 |
| ▸ | MAOA | P21397 | 2/20 | 0.65 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.53 |
| ▸ | FADS1 | O60427 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918216 | 0.88 | NPC1 (0.62) | MAOBKLKB1METMAPTTP53 | |
| SCHEMBL27918087 | 0.88 | MAOB (0.65) | MAOBMAOAKLKB1METMAPT | |
| SCHEMBL27918116 | 0.87 | FADS1 (0.65) | MAOBMAOAKLKB1METFADS1 | |
| SCHEMBL27936544 | 0.85 | MAPT (0.60) | MAOBMAOAKLKB1METMAPT | |
| SCHEMBL27918126 | 0.83 | MAOB (0.58) | MAOBMAOAKLKB1MAPTNPC1 | |
| SCHEMBL27936581 | 0.82 | KLKB1 (0.78) | KLKB1MET | |
| SCHEMBL27918218 | 0.81 | KLKB1 (0.56) | MAOBKLKB1METMAPTTP53 | |
| SCHEMBL27771283 | 0.80 | FADS1 (0.67) | MAOBMAOAMETFADS1NPC1 | |
| SCHEMBL10600292 | 0.78 | MAOB (0.69) | MAOBMAOANPC1ALDH1A1RAB9A | |
| SCHEMBL21221792 | 0.76 | RXRA (0.68) | MAOBMAOANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | claimed |
| CN-103304438-B | N-substituted salicylamide compounds, preparation method and application | SHANDONG UNIVERSITY (CN) | 2015-12-02 | — | — | CN | disclosed |
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | disclosed |