Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 7/20 | 0.78 |
| ▸ | PLG | P00747 | 11/20 | 0.64 |
| ▸ | KLK1 | P06870 | 11/20 | 0.64 |
| ▸ | KLK6 | Q92876 | 10/20 | 0.64 |
| ▸ | PLAU | P00749 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | PLAT | P00750 | 1/20 | 0.56 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918218 | 0.85 | KLKB1 (0.56) | KLKB1PLAUF2F10PLAT | |
| SCHEMBL27918216 | 0.84 | NPC1 (0.62) | KLKB1MET | |
| SCHEMBL27936605 | 0.82 | MAOB (0.65) | KLKB1MET | |
| SCHEMBL27918087 | 0.82 | MAOB (0.65) | KLKB1MET | |
| SCHEMBL27918116 | 0.80 | FADS1 (0.65) | KLKB1MET | |
| SCHEMBL27936544 | 0.79 | MAPT (0.60) | KLKB1MET | |
| SCHEMBL21274699 | 0.78 | PLG (1.00) | KLKB1PLGKLK1KLK6PLAU | |
| SCHEMBL3210641 | 0.78 | MAOB (0.65) | — | |
| Hydrochloric Acid SCHEMBL22799450 | 0.77 | PLG (1.00) | KLKB1PLGKLK1KLK6PLAU | |
| SCHEMBL3900807 | 0.76 | CA12 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | claimed |
| CN-103304438-B | N-substituted salicylamide compounds, preparation method and application | SHANDONG UNIVERSITY (CN) | 2015-12-02 | — | — | CN | disclosed |
| CN-103304438-A | N-substituted salicylamide type compound as well as preparation method and application thereof | UNIV SHANDONG | 2013-09-18 | — | — | CN | disclosed |