SCHEMBL2791966

SCHEMBL2791966

C=C(c1cccc([C@@H](Cl)CCc2ccccc2C(C)(C)O)c1)c1ccc2ccc(Cl)cc2n1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.44
▸ RECQL P46063 1/20 0.44
▸ BLM P54132 1/20 0.44
▸ KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1592247 0.85 CBLB (0.34) —
SCHEMBL1400950 0.85 CBLB (0.34) —
SCHEMBL5498778 0.83 POLB (0.40) —
SCHEMBL1401053 0.82 PLA2G2A (0.36) —
SCHEMBL2792722 0.80 MEN1 (0.36) MEN1RECQLBLMKMT2A
SCHEMBL1592780 0.79 CYSLTR1 (0.66) MEN1RECQLBLMKMT2A
SCHEMBL2791965 0.79 CYSLTR1 (0.66) MEN1RECQLBLMKMT2A
SCHEMBL28954752 0.79 CYSLTR1 (0.66) MEN1RECQLBLMKMT2A
SCHEMBL5214449 0.75 — —
SCHEMBL9339015 0.74 CBLB (0.41) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100168432-A1 Process for the Preparation of Montelukast MATRIX LABORATORIES LTD (IN) 2010-07-01 — — US claimed
EP-1940793-A2 A PROCESS FOR THE PREPARATION OF MONTELUKAST Matrix Laboratories Ltd (IN) 2008-07-09 — — EP claimed
WO-2007004237-A2 A PROCESS FOR THE PREPARATION OF MONTELUKAST MATRIX LABORATORIES LTD (IN) 2007-01-11 — — WO claimed
US-20100168432-A1 Process for the Preparation of Montelukast MATRIX LABORATORIES LTD (IN) 2010-07-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100168432-A1 Process for the Preparation of Montelukast CMA1, MPST, MED1 MEN1 2668/4885RECQL 4474/4885BLM 4626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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