SCHEMBL1400950

SCHEMBL1400950

C=C(c1cccc([C@@H](Cl)CCc2ccccc2CC(C)O)c1)c1ccc2ccc(Cl)cc2n1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1592247 1.00 CBLB (0.34) CBLB
SCHEMBL5214449 0.90 — —
SCHEMBL2791966 0.85 MEN1 (0.44) —
SCHEMBL5498778 0.84 POLB (0.40) —
SCHEMBL1401053 0.82 PLA2G2A (0.36) CBLB
SCHEMBL9339015 0.79 CBLB (0.41) CBLB
SCHEMBL5493627 0.76 POLB (0.38) —
SCHEMBL3773863 0.76 PLA2G2A (0.36) CBLB
SCHEMBL1401179 0.76 PLA2G2A (0.36) CBLB
SCHEMBL5502331 0.74 POLB (0.38) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1812394-A2 PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS SALTS Matrix Laboratories Ltd (IN) 2007-08-01 — — EP claimed
WO-2006008751-A2 PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS SALTS MATRIX LABORATORIES LTD (IN) 2006-01-26 — — WO claimed
US-20110137039-A1 PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS SALTS MYLAN LABORATORIES LIMITED (IN) 2011-06-09 — — US disclosed
EP-1812394-B1 PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS SALTS MATRIX LAB LTD (IN) 2011-03-02 — — EP disclosed
US-20090143590-A1 Process for the Preparation of Montelukast and its Salts MATRIX LABORATORIES LTD. (IN) 2009-06-04 — — US disclosed
EP-1812394-A2 PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS SALTS Matrix Laboratories Ltd (IN) 2007-08-01 — — EP disclosed
WO-2006008751-A2 PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS SALTS MATRIX LABORATORIES LTD (IN) 2006-01-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090143590-A1 Process for the Preparation of Montelukast and its Salts CMA1, CYSLTR1, CYSLTR2 CBLB 4465/4885
US-20110137039-A1 PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS SALTS MPST, CMA1, LTC4S CBLB 2747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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