Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RORB | Q92753 | 3/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269858 | 0.86 | KDM4E (0.53) | KDM4EPKMRORBSMN1; SMN2CDC7 | |
| SCHEMBL27582958 | 0.82 | KDM4E (0.43) | KDM4EPKMRORBSMN1; SMN2NPC1 | |
| SCHEMBL24509432 | 0.82 | RORB (0.46) | KDM4EPKMRORBSMN1; SMN2NPC1 | |
| SCHEMBL24508661 | 0.82 | ALDH1A2 (0.47) | KDM4EPKMCDC7DBF4NPC1 | |
| Hydrochloric Acid SCHEMBL27583077 | 0.81 | KDM4E (0.42) | KDM4EPKMRORBSMN1; SMN2NPC1 | |
| SCHEMBL17843997 | 0.80 | KDM4E (0.45) | KDM4EPKMRORB | |
| SCHEMBL1561051 | 0.78 | KDM4E (0.46) | KDM4EPKMRORBSMN1; SMN2NPC1 | |
| SCHEMBL27653976 | 0.75 | RORB (0.55) | KDM4EPKMRORBCDC7DBF4 | |
| SCHEMBL28357565 | 0.75 | KDM4E (0.41) | KDM4EPKM | |
| SCHEMBL27727758 | 0.75 | STK33 (0.48) | KDM4EPKMNPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103333134-A | 2-(3-cyano-4-alkoxy) phenyl-4-substituted thiazole-5-formic acid compound, composition as well as preparation methods and applications thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-10-02 | — | — | CN | claimed |
| CN-103333134-B | 2-(3-cyano group-4-alkoxyl group) phenyl-4-substituted thiazole-5-formic acid compound, composition and method of making the same and purposes | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2016-02-24 | — | — | CN | disclosed |
| CN-103333134-A | 2-(3-cyano-4-alkoxy) phenyl-4-substituted thiazole-5-formic acid compound, composition as well as preparation methods and applications thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-10-02 | — | — | CN | disclosed |